Difficulties In Managing Methemoglobinemia

Difficulties In Managing Methemoglobinemia

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Acute poisoning with nitrobenzene causing significant methemoglobinemia is a rare yet life-threatening emergen-cy.A 20-year-old, female presented to Emergency in altered sensorium with a history of Unframed Football Photos consumption of a bioor-ganic formulation.On examination she was cyanosed restless and agitated with SpO2 of 70% on room air.

Blood samples drawn for ABG was chocolate brown colour on blotting paper.ABG showed metabolic acidosis with a satu-ration of 80%.Methylene blue 50mg in IV saline was given over 5 mins and oral ascorbic acid.

She improved slowly after the 9th day with SpO2 of 92% on room air.She was discharged on the 17th day on oral iron, ascorbic acid, and breathing exercises.Early aggressive management of #10 Star Washer severe poisoning, strongly suspected on clinical grounds may change the outcome of the patient.

Key-words: Nitrobenzene, methemoglobinemia, methylene blue, pulse oximetry.